Paraxanthine
01 · Cognitive & Brain Health

Paraxanthine

Brain Activation · Athletic Performance · The Next-Generation Innovative Ingredient That Fully Replaces Caffeine

Key Selling Points
  • Advanced Manufacturing
  • Comprehensive Quality Control
  • cGMP-Compliant Manufacturing
  • Excellent Formulation Compatibility
  • Significantly Enhanced Safety

02Product Description

Purity
98.0 Min
Appearance
White crystalline powder
CAS No.
611-59-6
Molecular Formula
C7H8N4O2
Molecular Weight
180.16

03Product Specifications

Test ItemSpecificationMethod
Purity98.0 Min / 99.9%HPLC
Loss on drying1.0% Max / 0.26%USP
Residue on ignition1.0% Max / 0.88%USP
Heavy metals10ppm Max / ConformsAtomic Absorption
As1ppm Max / ConformsICP-MS
Pb0.5ppm Max / ConformsICP-MS
Cd0.5ppm Max / ConformsICP-MS
Hg0.1ppm Max / ConformsICP-MS
Microbiology Control
Total Plate Count1000 cfu/g Max / 100 cfu/g MaxUSP
Yeast & Mold100 cfu/g Max / 10 cfu/g MaxUSP

04Product Process & Advantages

Advanced Manufacturing

Produced using advanced separation and precision crystallization technologies to ensure a consistent purity of ≥98.0%.

Comprehensive Quality Control

Strict monitoring of heavy metals, microbial limits, pesticide residues, and residual solvents ensures compliance with international quality standards.

cGMP-Compliant Manufacturing

Manufactured in strict compliance with cGMP standards, with comprehensive documentation provided, including CoA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and declarations of TSE/BSE-free (Transmissible Spongiform Encephalopathy) and allergen-free status.

Excellent Formulation Compatibility

With excellent water solubility and powder flowability, it is suitable for a wide range of dosage forms, including capsules, tablets, powders, gummies, and ready-to-drink (RTD) beverages.

Significantly Enhanced Safety

Compared to conventional caffeine, the acute toxicity potential of Paraxanthine is significantly reduced, providing a smoother energy experience.

More Consistent Consumer Response

As a primary metabolite of caffeine, Paraxanthine provides more predictable energy and focus support for a broader consumer base, including those sensitive to caffeine.

Lower Bitterness

Compared to caffeine, theobromine, and theophylline, Paraxanthine has a milder taste, helping to reduce the need for flavor masking in modern formulations.

05Product Functions & Mechanisms

More Potent Awakening and Stimulation

Similar to the mechanism of action of traditional caffeine, but with greater potency. Paraxanthine blocks adenosine receptors (particularly the A₁ and A₂A subtypes) more effectively, resulting in stronger physical stimulation and mental alertness while avoiding the discomfort associated with high doses of caffeine.

Rapid Clearance, No Accumulation, and No Sleep Interference

Among all common methylxanthine compounds, paraxanthine has the shortest half-life (approximately 3 hours) and the highest plasma clearance rate.

Compared to caffeine

Half-life is approximately 25% shorter (3.1h vs. 4.1h), with faster clearance.

Effect

“Fast-acting, fast-fading”—significantly boosts energy and focus during the day, with no residual effects in the body at night, leaving deep sleep structure and rhythms undisturbed.

Supports Cognitive Function and Brain Health

Research indicates that Paraxanthine not only enhances short-term memory and sustained attention but also exhibits potential neuroprotective effects to support long-term brain health and cognitive longevity.

Cardiovascular-Friendly with Reduced Anxiety

Paraxanthine does not cause noticeable anxiety, palpitations, or tachycardia like caffeine does. Its unique mechanism of action (involving cGMP-PDE regulation) allows it to provide “Clean Energy” while offering greater cardiovascular safety and avoiding side effects such as nausea and diarrhea commonly associated with other methylxanthines.

06Applications

  • Given its role in energy provision, anxiety relief, brain stimulation, fat burning, neuroprotection, and excellent pharmacokinetic safety, Paraxanthine has a wide range of applications. A typical recommended dosage of 100 to 300 milligrams per serving allows for a seamless and effortless replacement of caffeine in existing product lines:
  • Premium Sports Nutrition: Cutting-edge pre-workout pumps, endurance supplements, muscle power matrices, and marathon sports supplements.
  • Cognitive and Nootropic Dietary Supplements: Workplace focus capsules, student brain-boosting powders, and e-sports anti-fatigue energy tablets.
  • Innovative Functional Foods & Beverages: Clean energy drinks, upgraded ready-to-drink coffee, sugar-free keto sports drinks, and healthy herbal energy drinks
  • Formulation & Application Recommendations
  • Clean Energy & Pre-Workout Formula
  • Suggested Combination: Paraxanthine + L-Citrulline + AAKG 2:1 + Taurine
  • Pre-Workout / Sports Performance / Pump Formula
  • Formulation Benefits: Supports clean energy, nitric oxide production, workout focus, and endurance performance with a smoother stimulation experience compared with traditional caffeine systems.
  • Focus & Nootropic Formula
  • Suggested Combination: Paraxanthine + Alpha-GPC + L-Theanine + Huperzine A
  • Nootropic Capsules / Gaming Formula / Productivity Support
  • Formulation Benefits: Designed to support focus, mental clarity, reaction speed, and cognitive performance while helping reduce overstimulation.
  • Thermogenic & Clean Energy Formula
  • Suggested Combination: Paraxanthine + Capsicum Extract (Capsaicinoids) + Ginger Extract + L-Carnitine
  • Fat Burner / Weight Management / Metabolic Support

07Packaging & Storage

  • Packaging specifications: Standard 25 kg cardboard drums (lined with double-layer moisture-proof PE bags); custom small-batch packaging for pilot testing and R&D is available.
  • Storage conditions: Keep tightly sealed and store in a cool, dry, well-ventilated area away from light, heat, and moisture.
  • Shelf life: 24 months.

08Frequently Asked Questions

What is the CAS number of Paraxanthine?

The CAS number of Paraxanthine is 611-59-6.

What purity of Paraxanthine do you supply?

AIDU Biotech supplies Paraxanthine at 98.0 Min, with full analytical data and a Certificate of Analysis (COA) for every batch.

Do you provide a COA and third-party testing for Paraxanthine?

Yes. Every batch of Paraxanthine ships with a complete Certificate of Analysis (COA), and we provide MSDS and third-party test reports on request.

Can you ship Paraxanthine from a US warehouse?

Yes. AIDU Biotech keeps inventory in our Los Angeles, USA warehouse for faster North American delivery, alongside global shipping from our own manufacturing facility.

What is the minimum order quantity (MOQ) for Paraxanthine?

MOQ and bulk pricing vary by grade and volume. Contact idusc@aidubio.com for free samples and a quote.

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+86-21-61049330 · +86-138-1774-6068
idusc@aidubio.com
Warehouse Address: Los Angeles, CA, USA

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