RejuEGT® L-Ergothioneine
RejuEGT® L-Ergothioneine

RejuEGT® L-Ergothioneine

The gold standard of nature for cellular longevity and system-level protection

CAS No.: 497-30-3
Product Appearance: White to off-white powder
Product Specification: 99.5% MIN

01Product Description

RejuEGT® is a high-purity natural L-Ergothioneine product independently developed and registered as a trademark by Shanghai Aidu Biotechnology. L-Ergothioneine, as a naturally occurring sulfur-containing amino acid derivative, has garnered widespread attention in recent years across fields such as healthy aging, cognitive health, sports nutrition, functional foods, and high-end skincare, owing to its outstanding antioxidant and cytoprotective capabilities.

Aidu Biotech employs a novel proprietary fermentation technology to produce high-purity L-Ergothioneine. Leveraging advanced bio-fermentation processes, the company ensures high product stability, consistency, and sustainable large-scale production, thereby meeting the demand for high-quality raw materials in the global dietary supplement, functional food, and cosmetics markets.

02Core Technical Advantages

Multi-pathway Synthesis Technology: AIDU Biotech has mastered chemical (non-GMO), enzymatic, and fermentation synthesis technologies, boasting a production capacity of tens of tons, and is capable of flexibly adapting to the regulatory requirements of different countries worldwide.

Ultimate Quality Assurance: The product obtained through Aidu Biotech's process is a white powdery crystal, stable and non-hygroscopic, with excellent water solubility, and both purity and content reaching up to 99.5%.

Rigorous Safety Validation: The product is classified as practically non-toxic. According to the 90-day oral toxicity test, the No Observed Adverse Effect Level (NOAEL) exceeds 150 mg/kg BW/d.

03Core Benefits

Antioxidant Defense

Neuroprotective Support

Memory & Cognitive Support

Cardiovascular Support

Mitochondrial Function Support

Inflammatory Response & Skin Protection

04Scientific Mechanism: From Antioxidant Protection to Cellular Energy Support

RejuEGT® is a functional antioxidant ingredient recognized for its targeted cellular protective properties.In selected in vitro antioxidant assays, RejuEGT® has demonstrated significantly stronger free radical scavenging activity compared with Coenzyme Q10, Glutathione, and Vitamin C.

In addition, it has been extensively studied in the fields of mitochondrial health, neuroprotection, and cellular oxidative defense.

  • Reactive Oxygen Species (ROS) Defense

Helps neutralize excess free radicals and reactive oxygen species (ROS), supporting cellular oxidative balance.

  • Mitochondrial Function Support

Supports mitochondrial integrity and cellular energy metabolism under oxidative stress conditions.

  • Neuroprotective Support

Helps protect neuronal cells from oxidative stress, supporting cognitive performance and healthy aging.

  • Oxidative Stress & Inflammatory Response Modulation

Supports cellular defense against UV-induced oxidative stress and related inflammatory signaling.

05Technical Specifications

*Based on typical batch data for 99.5% grade

ItemSpecificationTest Method
Purity99.5%MinHPLC
Assay99.% ~101%HPLC
Loss on drying0.5% MaxUSP
Melting Point270~271℃Melting Point detector
Optical Rotation[α]D≥ (+)122°(c=1, H2O)Polarimeter (c=1, H2O)
Heavy metals10ppm MaxUSP
Pb0.1ppm MaxICP-MS
As0.1ppm MaxICP-MS
Hg0.1ppm MaxICP-MS
Cd0.1ppm MaxICP-MS
Ethanol residue300ppm MaxGC
Mesh100% pass rate for 50 meshSieve
Total Plate Count100cfu/g MaxUSP
Mold and yeast100cfu/g MaxUSP

06Application Directions & Solutions

RejuEGT® (L-Ergothioneine), with its outstanding stability and bioactivity, can synergize with a variety of functional ingredients to deliver targeted solutions for the following areas:

  • Longevity, Anti-aging & Mitochondrial Support: Recommended to be combined with α-Lipoic Acid (ALA), NMN, and Glutathione. Ideal for high-purity longevity management capsules or precision supplements.
  • Brain Health & Cognitive Support: Recommended to be paired with GABA and Cysteine, aiming to protect neurons and enhance memory resilience.
  • Oral Beauty & Premium Skincare: Combined with Glutathione, Vitamin C, etc., to achieve endogenous repair by inhibiting tyrosinase and fighting photoaging.
  • Sports Nutrition & Recovery: Provides mitochondrial-level repair for exercise-induced oxidative stress, supporting muscle recovery.

07Compliance & Global Supply

Certification Systems: GMP, Self-GRAS, FDA GRAS etc.

Clean Label: Non-GMO, Stable Batch Supply, Traceable Production

Global Supply: Supporting long-term stable supply and customized needs for the international market

U.S. Trademark & Commercial Compliance:

Official Trademark Registration: Protected under U.S. Trademark Serial No. 98568732 by Shanghai Aidu Biotechnology Co., Ltd.

Proven Commercialization: Successfully introduced and actively commercialized in U.S. commerce since March 26, 2025, offering verified batch consistency and regulatory peace of mind for global brand formulators.

Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. For B2B commercial use only.

08Frequently Asked Questions

What is the CAS number and purity of RejuEGT®?

RejuEGT® L-Ergothioneine is CAS 497-30-3, supplied as a white to off-white powder at 99.5% minimum purity.

Which production route do you use — fermentation or synthesis?

We have mastered chemical (non-GMO), enzymatic and fermentation routes, with tens of tons of capacity, so the route can be matched to the regulatory requirements of your target market.

Is there safety and regulatory documentation available?

Yes. The product is classified as practically non-toxic with a 90-day oral toxicity NOAEL above 150 mg/kg BW/d, and is supported by GMP, Self-GRAS and FDA GRAS documentation plus a batch-specific COA.

How fast can you deliver in the U.S. and what is the MOQ?

We ship from local U.S. inventory in Los Angeles, CA as well as from China. Send your target volume and application to idusc@aidubio.com for MOQ, pricing and samples.

GET IN TOUCH

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Tell us the ingredient and volume you need. Our team will respond with pricing, lead time and documentation.

+86-21-61049330 · +86-138-1774-6068
idusc@aidubio.com
Warehouse Address: Los Angeles, CA, USA

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