DHMSober™ Premium Dihydromyricetin

DHMSober™ — Premium Dihydromyricetin

DHMSober™ is a proprietary brand of Dihydromyricetin (DHM) developed by Shanghai Aidu Biotechnology Co., Ltd. This ingredient is derived from the widely distributed Vine Tea plant (Ampelopsis grossedentata) in Asia and belongs to naturally occurring flavonoid compounds.

Dihydromyricetin (DHM) is a naturally occurring polyphenolic flavonoid with well-defined botanical origins, primarily extracted from Vine Tea (Ampelopsis grossedentata) and also detectable in specific plants such as Hovenia dulcis. As one of the traditional botanical ingredients, DHM has a long history of traditional use in East Asia. In recent years, Recent studies have investigated DHM at molecular and metabolic levels, focusing on its potential roles in alcohol metabolism pathways, oxidative stress regulation, and hepatic metabolic homeostasis, providing scientific references for its application in nutritional and functional formulations.

Plant Part: Stem and Leaf

Available Specifications: 50%, 98%

(*The purity of technical indicators in the table is 98%)

• Biotech's own production facilities in accordance with applicable cGMP requirements. The products comply with quality criteria such as Non-GMO, Solvent-free, and Gluten-free. Each batch undergoes comprehensive physicochemical testing before release and is verified by international third-party laboratories like Eurofins, providing strong support for compliance in major global health markets including the U.S. and EU.
• Reliable Supply and Delivery: Leveraging a mature domestic raw material production system combined with local warehousing and logistics resources in the U.S., AIDU Biotech offers global customers stable supply, inventory support, and efficient delivery services for DHM raw materials, meeting the demands of large-scale production and long-term supply programs.

• Rapid Hangover Relief: Dihydromyricetin (DHM) significantly enhances the liver's ability to metabolize alcohol. By boosting the activity of Alcohol Dehydrogenase (ADH) and Acetaldehyde Dehydrogenase (ALDH) in the liver, it accelerates the breakdown of the toxic metabolite "acetaldehyde," effectively reducing post-drinking fatigue and headaches.
• Liver Protection & Lipid Balance: DHM is widely used in liver nutritional support. Studies show that it protects hepatocytes from alcohol-induced damage and maintains healthy cellular homeostasis by regulating lipid metabolism.
• Enhanced Antioxidant Capacity: As a potent natural flavonoid, DHM provides deep metabolic support. It actively participates in free radical-scavenging pathways, significantly reducing oxidative stress damage in the body.
• Improved Physical Performance & High-Altitude Adaptation: Scientific research confirms that DHM aids in post-exercise recovery and enhances the body’s adaptation to simulated high-altitude hypoxic environments, providing a scientific foundation for physical performance support products.

Scientific Research & Data Backing

DHMSober™ by AIDU Biotech is not only a natural solution for alcohol detoxification but also a precise regulator of cellular energy metabolism and liver protection.

1 Cellular Metabolic Regulation & Energy Pathway Support (AMPK / Sirtuins Signaling Pathways): Studies have shown that in alcohol-loaded animal models, DHM participates in regulating AMPK and Sirt-1-related signaling pathways, influencing the expression levels of downstream PGC-1α. This mechanism is closely associated with mitochondrial function maintenance and cellular energy metabolic homeostasis.

2 Mitochondrial Function and Hepatic Energy Metabolism Research (Mitochondrial Biogenesis & ATP Production):

Experimental studies have shown that the DHM-treated group exhibits upregulated expression of mitochondrial-related proteins and improved energy metabolic indicators in liver tissue.

• Energy Optimization: Effectively reverses alcohol-induced decline in ATP production.
• Cellular Repair: Significantly upregulates PGC-1α expression, promotes mitochondrial biogenesis, and enhances overall cellular energy output.

Literature References:

• Shen, Y., et al. (2020). Dihydromyricetin improves mitochondrial outcomes in alcohol-fed mice via AMPK/Sirt-1/PGC-1α signaling. Toxicology and Applied Pharmacology. [DOI: 10.1016/j.taap.2020.115000]
• Shen, Y., et al. (2012). Dihydromyricetin as a Novel Anti-Alcohol Intoxication Medication. Journal of Neuroscience.
• Zhang, Y., et al. (2014). Dihydromyricetin Improves Physical Performance under Simulated High Altitude. Medicine & Science in Sports & Exercise.

• Dietary Supplements: As a core functional ingredient, it is applied in dietary supplement formulations for alcohol detoxification (alcohol metabolism support), long-term liver protection, and daily metabolic balance.
• Functional Foods & Beverages: Suitable for developing "anti-hangover drinks" or "liver-protecting beverages" targeting social scenarios, supporting product designs that enhance metabolic vitality and reduce post-drinking discomfort.
• Sports Nutrition & Performance Recovery: Used in formulation systems aimed at post-exercise fatigue recovery and high-altitude adaptation, meeting the demand for physical performance support ingredients in the sports industry and among high-intensity work populations.
• Scientific Research & Product Development: As an efficient natural flavonoid derivative raw material, it is applied in basic pharmacological research, mitochondrial metabolic pathway exploration, and functional validation stages of health product development.

Packaging Specification: Standard is 25kg/drum, with double inner aluminum bags, or customized according to customer requirements.

Storage Conditions: Sealed storage, protected from moisture and light.

Shelf Life: 36 months.