DHMSober™ is a proprietary brand of Dihydromyricetin (DHM) developed by Shanghai Aidu Biotechnology Co., Ltd. This ingredient is derived from the widely distributed Vine Tea plant (Ampelopsis grossedentata) in Asia and belongs to naturally occurring flavonoid compounds.
| Test Item | Specification | Method |
|---|---|---|
| Assay | 98.0% Min | HPLC |
| Identification | Passes all criteria tests | |
| TLC | ||
| Loss on drying | 3.0% Max | USP |
| Ash | 0.2% Max | USP |
| Sieve analysis | 80 Mesh | USP |
| Pb | 0.5ppm Max | ICP-MS |
| As | 1.0ppm Max | ICP-MS |
| Hg | 0.1ppm Max | ICP-MS |
| Cd | 0.5ppm Max | ICP-MS |
| Microbiology Control | ||
| Total Plate Count | 1000cfu/g Max | USP |
| Yeast&Mold | 100cfu/g Max / USP / (*The purity of technical indicators in the table is 98%) | |
Dihydromyricetin (DHM) is a naturally occurring flavonoid compound with multiple phenolic hydroxyl groups, demonstrating favorable stability in metabolic studies. Its molecular structure enables participation in various physiological pathways related to oxidative stress and metabolic regulation, making it suitable for applications supporting alcohol metabolism, liver nutrition, and functional formulation development.
AIDU Biotech employs standardized plant extraction and multi-step refining processes to obtain high-purity DHM from premium botanical sources. Through controlled extraction, purification, and refinement procedures, key quality parameters are rigorously managed to ensure product purity ≥98% and controlled impurity levels, meeting the consistency and safety requirements for dietary supplements and functional ingredients.
All DHM raw materials are manufactured at AIDU Biotech's own production facilities under strict cGMP quality management standards. The products comply with quality criteria such as Non-GMO, Solvent-free, and Gluten-free. Each batch undergoes comprehensive physicochemical testing before release and is verified by international third-party laboratories like Eurofins, providing strong support for compliance in major global health markets including the U.S. and EU.
Leveraging a mature domestic raw material production system combined with local warehousing and logistics resources in the U.S., AIDU Biotech offers global customers stable supply, inventory support, and efficient delivery services for DHM raw materials, meeting the demands of large-scale production and long-term project collaborations.
Dihydromyricetin (DHM) significantly enhances the liver's ability to metabolize alcohol. By boosting the activity of Alcohol Dehydrogenase (ADH) and Acetaldehyde Dehydrogenase (ALDH) in the liver, it accelerates the breakdown of the toxic metabolite "acetaldehyde," effectively reducing post-drinking fatigue and headaches.
DHM is widely used in liver nutritional support. Studies show that it protects hepatocytes from alcohol-induced damage and maintains healthy cellular homeostasis by regulating lipid metabolism.
As a potent natural flavonoid, DHM provides deep metabolic support. It actively participates in free radical-scavenging pathways, significantly reducing oxidative stress damage in the body.
Improved Physical Performance & High-Altitude Adaptation: Scientific research confirms that DHM aids in post-exercise recovery and enhances the body’s adaptation to simulated high-altitude hypoxic environments, providing a scientific foundation for physical performance support products.
DHMSober™ by AIDU Biotech is not only a natural solution for alcohol detoxification but also a precise regulator of cellular energy metabolism and liver protection.
Cellular Metabolic Regulation & Energy Pathway Support (AMPK / Sirtuins Signaling Pathways): Studies have shown that in alcohol-loaded animal models, DHM participates in regulating AMPK and Sirt-1-related signaling pathways, influencing the expression levels of downstream PGC-1α. This mechanism is closely associated with mitochondrial function maintenance and cellular energy metabolic homeostasis.
Mitochondrial Function and Hepatic Energy Metabolism Research (Mitochondrial Biogenesis & ATP Production):
Experimental studies have shown that the DHM-treated group exhibits upregulated expression of mitochondrial-related proteins and improved energy metabolic indicators in liver tissue.
Effectively reverses alcohol-induced decline in ATP production.
Significantly upregulates PGC-1α expression, promotes mitochondrial biogenesis, and enhances overall cellular energy output.
Literature References:
Shen, Y., et al. (2020). Dihydromyricetin improves mitochondrial outcomes in alcohol-fed mice via AMPK/Sirt-1/PGC-1α signaling. Toxicology and Applied Pharmacology. [DOI: 10.1016/j.taap.2020.115000]
Shen, Y., et al. (2012). Dihydromyricetin as a Novel Anti-Alcohol Intoxication Medication. Journal of Neuroscience.
Zhang, Y., et al. (2014). Dihydromyricetin Improves Physical Performance under Simulated High Altitude. Medicine & Science in Sports & Exercise.
The CAS number of DHMSober™ Dihydromyricetin is 27200-12-0.
AIDU Biotech supplies DHMSober™ Dihydromyricetin at 98.0% Min, with full analytical data and a Certificate of Analysis (COA) for every batch.
Yes. Every batch of DHMSober™ Dihydromyricetin ships with a complete Certificate of Analysis (COA), and we provide MSDS and third-party test reports on request.
Yes. AIDU Biotech keeps inventory in our Los Angeles, USA warehouse for faster North American delivery, alongside global shipping from our own manufacturing facility.
MOQ and bulk pricing vary by grade and volume. Contact idusc@aidubio.com for free samples and a quote.
Tell us the ingredient and volume you need. Our team will respond with pricing, lead time and documentation.
