
Apigenin | A Natural Flavonoid Ingredient for Sleep Support and Healthy Aging Formulations
| Test Item | Specification | Method |
|---|---|---|
| Assay | 99.0% Min / 100.0% | HPLC |
| Loss on drying | 5.0% Max / 0.69% | USP |
| Ash | 1.0% Max / 0.09% | USP |
| Heavy metals | 10ppm Max / Conforms | USP |
| As | 0.5ppm Max / Conforms | USP |
| Pb | 0.5ppm Max / Conforms | USP |
| Cd | 0.5ppm Max / Conforms | USP |
| Hg | 0.1ppm Max / Conforms | USP |
| Particle Size | 95% pass 80 mesh / Conforms | USP |
| Bulk density | 0.18g/ml / 0.29g/ml | USP |
| Microbiology Control | ||
| Total Plate Count | 1000 cfu/g Max / Conforms | USP |
| Yeast & Mold | 100 cfu/g Max / Conforms | USP |
Using Citrus aurantium L. extract as the precursor material, this product is manufactured through a semi-synthetic process combined with multi-step purification and crystallization. This ensures high purity and stability control, making it suitable for large-scale supply and high-standard quality management requirements.
Excellent Physicochemical Properties and Formulation Compatibility
% of the product passes an 80-mesh sieve, with a bulk density of approximately 0.29 g/ml. It exhibits excellent flowability and dispersibility, making it suitable for the development of various dosage forms, including capsules, tablets, powders, gummies, and ready-to-drink (RTD) functional beverages.
Heavy metal and microbial limits comply with USP standards. We provide compliance declarations such as Non-GMO, Allergen-Free, and BSE/TSE-Free, meeting the quality management requirements of the dietary supplement and functional food sectors.
The product has low bitterness and minimal plant-derived off-flavors, helping to improve formulation palatability and reduce the complexity of flavor adjustment and masking system development. It is suitable for modern functional nutrition formulations.
Studies have shown that apigenin has certain associations with CD38 and NAD+ metabolic pathways. As a result, it has garnered significant attention in research on cellular energy metabolism, healthy aging, and mitochondrial function, and has been applied in the development of functional nutritional formulations.
Formulation Development for Relaxation and Nighttime Recovery
Due to its association with GABA_A receptor research, apigenin is widely used in formulations for nighttime recovery, relaxation support, and sleep health, addressing modern consumers’ demand for gentle nighttime nutritional solutions.
Apigenin continues to attract attention in research areas related to cellular health, oxidative stress, and inflammatory balance. Its association with signaling pathways such as NF-κB makes it one of the most sought-after natural flavonoid ingredients in the fields of healthy aging, skin health, and functional nutrition.
The CAS number of Apigenin is 520-36-5.
AIDU Biotech supplies Apigenin at 99.0% Min, with full analytical data and a Certificate of Analysis (COA) for every batch.
Yes. Every batch of Apigenin ships with a complete Certificate of Analysis (COA), and we provide MSDS and third-party test reports on request.
Yes. AIDU Biotech keeps inventory in our Los Angeles, USA warehouse for faster North American delivery, alongside global shipping from our own manufacturing facility.
MOQ and bulk pricing vary by grade and volume. Contact idusc@aidubio.com for free samples and a quote.
Tell us the ingredient and volume you need. Our team will respond with pricing, lead time and documentation.