Supermidine™ is a star ingredient developed by Aidu Biotech, tailored for the global longevity management market. We remain committed to direct extraction from premium non-GMO wheat germ, fully preserving the original structure of the plant's natural active molecules. As a potent autophagy inducer, spermidine leverages a cellular "clean-up" mechanism to efficiently eliminate damaged proteins, standing as a cutting-edge core ingredient in the fields of anti-aging, immune support, and metabolic management today.
| Test Item | Specification | Method |
|---|---|---|
| Text Method | Assay (Spermidine，on dried base) 1 / 1.0% Min / 1.11% | GC |
| Spermine | 0.3-1.2mg/g / 0.43mg/g | GC |
| Spermidine trichloride | 0.1μg/g Max | |
| Not Detected | — | GC |
| Putrescine | 0.3mg/g Max / 0.0454mg/g Max | GC |
| Cadaverine | 16.0μg/g Max | |
| Not Detected | — | GC |
| Loss on drying | 7.0% Max / 2.42% / USP<731> | |
| Ash | 5.0% Max / 2.66% / USP<281> | |
| Particle Size | 95% pass 80 mesh / Conforms / USP<786> | |
| Pb | 2ppm Max | |
| Not Detected | — | ICP-MS |
| As | 1ppm Max / 0.04ppm | ICP-MS |
| Hg | 0.1ppm Max / 0.003ppm Max | ICP-MS |
| Cd | 1ppm Max / 0.05ppm | ICP-MS |
| Bulk density | 0.4-0.6g/ml / 0.50/ml / USP / Mesh / 0.7-0.9g/ml / 0.80/ml | USP |
| Microbiology Control | ||
| Total Plate Count | 1000cfu/g Max / 10cfu/g Max | |
| AOAC | ||
| Mold and yeast | 100cfu/g Max / 10cfu/g Max | |
| AOAC | ||
Golden Specifications: Available in multiple specifications, including 0.2%, 0.5%, and 1% Min.
The core 1.0% specification is 100% derived from pure natural extraction from wheat germ, not synthetically produced. It boasts higher bioavailability and perfectly meets the strict demands of high-end brands for "Clean Label" and natural health.
Independent Laboratory Testing and Fully Transparent Quality Assurance
Equipped with an independent laboratory, we conduct strict testing on core indicators such as content (GC/HPLC), microorganisms, and heavy metals.
Each batch is accompanied by a detailed independent Certificate of Analysis (COA) with the shipment, ensuring that the residues of heavy metals (lead, arsenic, mercury, cadmium) and pathogenic bacteria are far below international general standards, supporting global traceability and auditing.
Excellent Physical Properties and Formulation Stability
Presented as a brownish-yellow powder with uniform particles, it features excellent fluidity and solubility.
It performs exceptionally when compounded with ingredients like NMN and Ergothioneine (RejuEGT®), and is suitable for various dosage forms such as capsules, tablets, and powders.
Activating Cellular AutophagyDelaying Aging and Supporting LongevityPromoting Hair and Skin HealthSupporting Cognitive Function
Natural Autophagy Activation and Anti-Inflammatory Pathways
The core mechanism of Supermidine™ is to induce autophagy — a physiological process of cellular self-cleansing, renewal and repair. With aging, autophagy function declines, leading to the accumulation of damaged cells and chronic inflammation, also known as inflammaging.
Spermidine induces the formation of autolysosomes by inhibiting EP300 acetyltransferase and other non-mTOR-dependent pathways, thereby promoting the clearance of intracellular waste components.
It facilitates the removal of dysfunctional mitochondria, reduces the leakage of mitochondrial reactive oxygen species (mtROS), and preserves the integrity of mitochondrial DNA.
Detailed functional and mechanism data available upon request.
Yes. Every batch of Supermidine™ Spermidine Wheat Germ Extract ships with a complete Certificate of Analysis (COA), and we provide MSDS and third-party test reports on request.
Yes. AIDU Biotech keeps inventory in our Los Angeles, USA warehouse for faster North American delivery, alongside global shipping from our own manufacturing facility.
MOQ and bulk pricing vary by grade and volume. Contact idusc@aidubio.com for free samples and a quote.
Tell us the ingredient and volume you need. Our team will respond with pricing, lead time and documentation.
