β-Nicotinamide Mononucleotide (NMN)

β-Nicotinamide Mononucleotide (NMN)

The direct NAD+ precursor for longevity and cellular energy formulations

Appearance: White to off-white powder
Solubility: Freely soluble in water and methanol
CAS Number: 1094-61-7
Molecular Weight: 334.22
Molecular Formula: C₁₁H₁₅N₂O₈P

01Product Description

NMN, short for β-nicotinamide mononucleotide, is a nucleotide naturally present in living organisms and serves as the direct precursor to NAD+. NAD+ is an essential coenzyme involved in human metabolic activities. As we age, the levels of NAD+ in the body gradually decline. Research has shown that oral intake of NMN is the most effective way to replenish NAD+, which can activate the longevity protein Sirtuins, boost immunity, and alleviate symptoms of aging.

02Product Specifications

Test ItemsSpecificationsTest Method
Purity99.5% MinHPLC
Assay (Dry Basis)99.0%-102.0% MinHPLC
PH(1.0g/100mL(25℃)3.0-4.5CP
Appearance of solution5%w/v in water: Colorless to pale yellow and clearOrganoleptic
Heavy Metals10ppm MaxUSP
Pb0.1ppm MaxICP-MS
As0.1ppm MaxICP-MS
Hg0.1ppm MaxICP-MS
Cd0.1ppm MaxICP-MS
Microbiology Control
Total Plate Count100cfu/g MaxUSP
Yeast&Mold100cfu/g MaxUSP

03Product Process and Advantages

  • Whole-Enzyme Catalysis Process: Aidu Biotech employs a unique biocatalytic (enzymatic) technology for targeted biosynthesis. Compared to chemical synthesis, our process produces no chiral impurities or isomers, contains no heavy metal residues, and delivers superior safety.
  • Ultra-High Stability: By optimizing the separation and purification process, we significantly reduce the product's hygroscopicity, ensuring enhanced chemical stability under ambient and high-humidity conditions. The particles are uniform with improved flowability, facilitating secondary development for capsules and tablets.
  • High Biological Activity: With 100% β-configuration, it is rapidly absorbed by human cells and efficiently converted into NAD+.
  • Large-Scale Supply: Backed by R&D in Shanghai and production facilities in Sichuan, our monthly capacity reaches 3–5 tons, supported by U.S.-based warehousing for rapid delivery.

04Product Functions and Mechanisms

NMN can directly enter cells via transporter proteins and be converted into NAD+ by NMNAT2. Alternatively, NMN may first be converted to nicotinamide riboside (NR) on the cell membrane surface, then taken up by cells in the form of NR, and subsequently converted into NAD+ through the actions of NRK and NMNAT2. Both NRKs and NMNATs are expressed across various organs and tissues, with the highest levels found in the liver.

Existing research data show that no abnormal fluctuations in serum aspartate aminotransferase (AST) or white blood cell count were observed in subjects five hours after oral administration of 500 mg NMN.

05Applications

  • Dietary Supplements: As the core active ingredient in high-end anti-aging capsules, powders, and tablets.
  • Life Science Research: A key biological reagent for laboratory studies on NAD+ metabolism and age-related degenerative diseases.
  • Functional Foods & Beverages: Added to medical foods or premium functional drinks as an energy-replenishing component.
  • Formulated Combinations: Typical synergistic pairings

NMN + TMG (Betaine) → Methyl donor balance

NMN + Resveratrol / Fisetin → NAD⁺ + Sirtuins synergy

NMN + CoQ10 / PQQ → Mitochondrial support

NMN + EGT (Ergothioneine) → Antioxidant + cellular protection

06Packaging & Storage

Packaging: 5kg/aluminum foil bag, 25kg/fiberboard drum (or customized upon request).

Storage Conditions: Keep tightly sealed and protected from light. For long-term storage, recommended temperature is 2–8°C.

Shelf Life: 24 months.

07Frequently Asked Questions

What is the CAS number and purity of your NMN?

NMN is CAS 1094-61-7, supplied at 99.5% minimum purity by HPLC with assay 99.0%-102.0% on a dry basis, in 100% β-configuration.

Is the NMN enzymatically produced or chemically synthesized?

It is produced by a whole-enzyme biocatalytic process, which avoids chiral impurities and isomers and leaves no heavy metal residues from synthesis.

What is your production capacity and lead time?

Monthly capacity is 3–5 tons from our Sichuan production base with R&D in Shanghai, plus U.S. warehousing in Los Angeles, CA for rapid domestic delivery.

How do I request a COA, sample or quotation?

Email idusc@aidubio.com with your target volume and packaging. Each lot ships with a batch COA covering purity, heavy metals by ICP-MS and microbiology.

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+86-21-61049330 · +86-138-1774-6068
idusc@aidubio.com
Warehouse Address: Los Angeles, CA, USA

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