Epimedium extract (also known as Horny Goat Weed extract) is a standardized herbal ingredient derived from Epimedium sagittatum, with icariin as its primary bioactive component. Icariin is widely recognized as a natural PDE5 inhibitor and is therefore commonly used in men’s health supplements, testosterone boosters, and sports nutrition formulations.
| Test Item | Specification | Method |
|---|---|---|
| Assay (Icariin) | 10.0% | HPLC |
| Extract solvents | 75%Ethanol & 25%Water | |
| / | ||
| Loss on drying | 5.0% Max | USP |
| Ash | 5.0% Max | USP |
| Sieve analysis | 80 Mesh | USP |
| Pb | 0.5ppm Max | ICP-MS |
| As | 1.0ppm Max | ICP-MS |
| Hg | 0.1ppm Max | ICP-MS |
| Cd | 0.5ppm Max / ICP-MS / 5000ppm Max | GC |
| Bulk density | 0.4g/ml Min | USP |
| Tapped density | 0.5g/ml Min | USP |
| Microbiology Control | ||
| Total Plate Count | 1000cfu/g Max | |
| USP-NF | ||
| Mold & Yeast | 100cfu/g Max | |
| USP-NF | ||
Standardized plant extraction, safe and controlled: Using Epimedium sagittatum as the raw material, we employ an ethanol-water extraction process to strictly control pesticide residues, heavy metals, and solvent residues, ensuring the product is natural, safe, and traceable. The entire process complies with GMP standards.
Utilizing HPLC analysis and multi-stage purification technology, we achieve stable Icariin content (10%–98%) with strong batch consistency, meeting the requirements for large-scale production and international market standards.
Low Impurity Profile, Enhanced Compliance:Through targeted purification processes, we effectively reduce non-target flavonoids and residual impurities, ensuring the product meets higher regulatory compliance and safety standards in European and American markets.
Physicochemical Stability, Suitable for Multiple Dosage Form Development: The powder exhibits excellent stability and flowability, making it suitable for various dosage forms such as capsules, tablets, gummies, and solid beverages, and supporting flexible development for different specifications and application scenarios.
Controllable Costs, Facilitating Commercialization: Leveraging mature processes and large-scale production capabilities, we optimize cost structures while ensuring quality, helping brand owners enhance product competitiveness and profit margins.
Icariin selectively inhibits phosphodiesterase type 5 (PDE5) activity, thereby increasing cGMP levels, enhancing NO signaling, and promoting vascular smooth muscle relaxation and improved blood flow.
Regulation of Testosterone Synthesis (Endocrine Support)
Icariin promotes testosterone synthesis and improves gonadal function by upregulating key proteins involved in steroidogenesis (such as StAR) and related enzymes (3β-HSD).
Icariin enhances the expression and activity of endothelial nitric oxide synthase (eNOS), increasing NO production and thereby improving vascular endothelial function.
Icariin promotes osteoblast differentiation and inhibits osteoclast formation, regulating bone metabolism through signaling pathways such as BMP-2 and Wnt.
Icariin possesses antioxidant and anti-inflammatory activity, reducing the expression of inflammatory factors such as TNF-α and IL-6, and mitigating oxidative stress damage.
Epimedium extract (Icariin) can be formulated with a variety of functional ingredients. Through synergistic effects across multiple pathways—including “blood flow regulation, hormonal support, and energy metabolism”—it is widely used in the development of products for men’s health, sports nutrition, and health management.
Epimedium extract + L-citrulline + Tongkat Ali
This combination synergistically regulates the nitric oxide (NO) pathway and endogenous hormone levels to support blood circulation and male physiological vitality, enhancing endurance and overall performance. It is currently the mainstream formulation for male health products.
Epimedium extract + Creatine + β-Alanine + L-Citrulline
By enhancing blood flow, boosting ATP energy metabolism, and alleviating lactic acid buildup, this formula achieves multidimensional improvements in “strength + endurance + pump sensation,” making it suitable for pre-workout and performance-enhancing product development.
The CAS number of Epimedium Extract is 489-32-7.
AIDU Biotech supplies Epimedium Extract at 10.0%, with full analytical data and a Certificate of Analysis (COA) for every batch.
Yes. Every batch of Epimedium Extract ships with a complete Certificate of Analysis (COA), and we provide MSDS and third-party test reports on request.
Yes. AIDU Biotech keeps inventory in our Los Angeles, USA warehouse for faster North American delivery, alongside global shipping from our own manufacturing facility.
MOQ and bulk pricing vary by grade and volume. Contact idusc@aidubio.com for free samples and a quote.
Tell us the ingredient and volume you need. Our team will respond with pricing, lead time and documentation.
