
Natural Aromatase Inhibitor · Men's Health Support · Innovative Ingredient for Sports Nutrition and Metabolic Management
As demand continues to grow in the global dietary supplement market for “natural hormone balance,” “sports recovery,” “healthy aging,” and “metabolic management,” traditional synthetic hormone-regulating ingredients are increasingly facing challenges due to safety concerns and regulatory restrictions. As a high-purity flavonoid compound derived from natural plants, Acacetin has garnered significant attention in recent years within the international sports nutrition, men’s health, weight management, and healthy aging sectors.
Given its research potential in aromatase inhibition, antioxidant activity, anti-inflammatory effects, metabolic support, and male hormone health management, Acacetin has gradually emerged as a leading ingredient in the next generation of natural sports nutrition ingredients and functional dietary supplements.


| Test Item | Specification Standard | Test Method |
|---|---|---|
| Assay | 98.0% Min | HPLC-AREA |
| Loss on drying | 1.0% Max | USP |
| Identification | Similar to working standard | HPLC |
| Heavy metals | 10ppm Max | USP |
| As | 1.0ppm Max | ICP-MS |
| Pb | 1.0ppm Max | ICP-MS |
| Cd | 1.0ppm Max | ICP-MS |
| Hg | 1.0ppm Max | ICP-MS |
| Residue on ignition | 0.20% Max | USP |
| Total Plate Count | 1000 cfu/g Max | GB4789.2-2022 |
| Yeast & Mold | 100 cfu/g Max | GB4789.15-2016 I |
We employ an advanced fully synthetic precision manufacturing process that combines multi-step purification with precision recrystallization technology. This eliminates risks associated with plant-derived pesticide residues, unknown impurities, and exogenous heavy metals at the source. It ensures consistent purity of ≥98.0% across batches (with typical batches reaching 99.9%). Production is completely free from seasonal and regional constraints, ensuring a stable supply chain and sufficient production capacity, which provides a solid foundation for stable, large-scale industrial-grade delivery.
Product purity is consistently maintained at 98.0% or higher. Through a proprietary powder modification process, particle size is strictly controlled. The powder exhibits excellent flowability, moisture resistance, and low bitterness. With low static charge and minimal tendency to adhere to walls, it is perfectly suited for the processing and development of various complex dosage forms, including hard capsule filling, tableting, solid beverage powders, functional gummies, and ready-to-drink (RTD) liquid beverages.
Production and quality control systems strictly adhere to international pharmacopoeia standards. For the fully synthetic process, solvent residue control fully complies with the limit requirements of USP <467> / EP. We maintain a comprehensive compliance documentation library and can quickly provide contracted clients with Non-GMO Declarations, Allergen-Free Certificates, BSE/TSE-Free Certificates, and complete batch COAs, significantly shortening the compliance approval cycle for your new products in overseas markets.
In recent years, Acacetin has garnered significant attention in the international market for men’s vitality and non-hormonal muscle support due to its outstanding research data in the field of aromatase inhibition. It is widely used in the development of cutting-edge formulations for high-end professional testosterone support, post-cycle therapy (PCT), and daily performance enhancement for men.
Multiple lines of scientific research indicate that Acacetin is closely associated at the cellular level with fatty acid oxidation, exercise metabolism regulation, and skeletal muscle energy utilization. This makes it a key differentiating ingredient in innovative sports nutrition products, including stimulant-free weight management formulas, high-efficiency thermogenic fat-burning products, and formulations designed to maintain lean muscle mass.
As a highly active natural flavonoid functional ingredient, Acacetin is closely linked to fundamental scientific research on regulating the NF-κB pathway, balancing oxidative stress, and maintaining healthy inflammatory responses in the body. This provides broad scope for innovation in its application within formulations for healthy aging, mitochondrial support, and premium comprehensive daily wellness nutrition.
Given the promising results demonstrated by acacetin in basic scientific research, the recommended single-dose addition for its formulations is typically 25 mg to 100 mg. Thanks to its process advantages of low dosage requirements and high stability, this ingredient can be seamlessly integrated into the following four major international high-end B2B product lines:
Formulations: Capsules / Tablets / Blended Powders
Formulations: Instant Powders / Capsules / RTD (Ready-to-Drink) Functional Beverages
Formulations: Capsules / Powder Sachets / Functional Beverages
Formulations: Capsules / Tablets / Functional Powders
Packaging specifications: 1 kg / aluminum foil bag, standard 25 kg / cardboard drum (lined with a double-layer moisture-proof PE bag); small-batch custom orders for pilot testing and R&D are available.
Storage conditions: Keep tightly sealed and store in a cool, dry, well-ventilated area away from light, heat, and moisture.
Shelf life: 24 months.
Acacetin is CAS 480-44-4, molecular formula C16H12O5, molecular weight 284.26. Specification is ≥98.0% by HPLC, with typical batches reaching 99.9%.
It is produced by a fully synthetic precision process with multi-step purification and recrystallization, which removes the risk of plant-derived pesticide residues and unknown impurities and makes supply independent of seasonal or regional constraints.
Based on published research, the typical single-dose addition is 25 mg to 100 mg per serving, adjusted to product positioning.
Non-GMO declarations, allergen-free certificates, BSE/TSE-free certificates and complete batch COAs; residual solvents comply with USP <467> / EP limits. Contact idusc@aidubio.com for documentation, MOQ and U.S. warehouse (Los Angeles, CA) delivery.
Tell us the ingredient and volume you need. Our team will respond with pricing, lead time and documentation.